Showing posts with label perimenopause. Show all posts
Showing posts with label perimenopause. Show all posts

Friday, April 27, 2012

They make you fat…and they aren’t food!


What do new car smell, your favorite fragrance, and a plastic bottle have in common? Well, while it sounds like a bad joke, it is quite serious. Each of these and many other common products contain substances called obesogens. That’s right, chemicals that initiate or propagate obesity. Of course, diet and exercise are still real contributors to weight, but the body composition equation runs a coefficient of hormone balance and obesogens disrupt hormone balance….sometimes in a big way!  And don’t think that just because you maintain healthy body weight that this doesn’t apply to you. Obesogens are endocrine disruptors and are the same chemicals that contribute to hormone issues such polycystic ovarian syndrome, amenorrhea, low testosterone, infertility, increased perimenopausal and menopausal symptoms, and certain cancers regardless of what the scale says.

Plasticizers leach from carpets and newly installed car interiors, thus providing that ever so pungent new car smell. In fact, when working with a hormone imbalance patient, I ask questions about exposure to new carpets and cars and after the weird looks, I get the story and excitement of a new “thing”, and then another weird look. Although, more often than not symptoms started or got worse after the new purchase.

If you’re thinking this is just another made up term to scare us or another excuse to rationalize dietary indiscretion, you would be misinformed. Obesogen is a term first coined in 2002 and since then has been cited in 19 peer-reviewed articles, with 6 of those published in 2011 and 4 already in 2012. It is gaining understanding and isn’t going away.

Much like we are learning that certain phytonutrients speak directly to our own genetic material, the hypothalamus, our master gland, and may either potentiate or interfere with enzymes, so too do these environmental chemicals.

The following are four truths as found in the Journal of Andrology:
  • “Obesogens are chemicals that directly or indirectly lead to increased fat accumulation and obesity. 
  • Obesogens have the potential to disrupt multiple metabolic signaling pathways in the developing organism that can result in permanent changes in adult physiology.
  • Prenatal or perinatal exposure to obesogenic endocrine disrupting chemicals has been shown to predispose an organism to store more fat from the beginning of its life.
  • This suggests that humans, who have been exposed to obesogenic chemicals during sensitive windows of development, might be pre-programmed to store increased amounts of fat, resulting in a lifelong struggle to maintain a healthy weight and exacerbating the deleterious effects of poor diet and inadequate exercise.”[1]

So it really may be true that some people are literally programmed to be fatter. However, that doesn’t mean that it is inevitable or uncontrollable. We are all dealt a different deck. Not all of us have the genetic material to be Olympic athletes and some that do, do not participate in the required training to compete, thus illustrating the contributions of both how we were made and what we’re exposed to. Where this becomes vitally important is during the reproductive years. Preconception programs often address helping moms-to-be and dads-to-be engage in healthy behaviors, optimizing hormone levels, improving detoxification, and reducing exposures to toxins. This is one such sensitive windows where obesogens can wreak havoc on metabolism…prior to conception!

The list of obesogens include phthalates also known as plasticizers are also found in personal care products such as shaving creams, colognes, and lotions, Bisphenol A (BPA) is found in plastic bottles and polyvinylchlorides found in shower curtains.

Recent changes at Whole Foods Market address possible concerns with obesogens. Dr. J. Renae Norton describes these changes in a two part series (Part I and Part II).

However, you can drive yourself crazy thinking about avoiding these chemicals. Most of them are released for absorption through your skin or ingested when plastics are heated. Avoiding hot plastics is a good step in the right direction but total avoidance is likely not possible with these nearly ubiquitous chemicals. Additionally, though, you can support the excretion of these chemicals through supporting liver, kidney, and bowel function on a daily basis.  Glutathione levels are perhaps most important if we zoom in single markers of the body. Glutathione acts as a free radical scavenger and also supports liver function. Without the bowel and kidneys functioning at their best, these chemicals cannot be eliminated. Supporting kidney function can be done with Sole therapy using Original Himalayan Crystal Salt and pH Quintessence on a daily basis. The pH Quintessence product also supports liver function, glutathione levels and bowel motility, making it a versatile and easy to use product. While obesogens may have programmed you to gain weight faster than normal and caused hormone imbalance, supporting the hypothalamus, the master gland, can help send the right signals to the right glands that need help the most while your body restores homeostasis. The hypothalamus talks to the pituitary gland and these two partners then communicate to the thyroid gland, pancreas, adrenal glands, ovaries, and testes. Natural Health International has introduced products for men well as different stages of life for women (Premenopausal, Perimenopausal, and Postmenopausal) to support comprehensive endocrine balance without introducing hormones from outside the body but rather supporting hypothalamus and pituitary function and all their downstream metabolic effects.

Obesogens are a serious chemical insult, but with some awareness of their effects, can be minimized and our bodies fully supported.


[1] Janesick A, Blumberg B. Obesogens, stem cells and the developmental programming of obesity. Int J Androl. 2012 Feb 28. doi: 10.1111/j.1365-2605.2012.01247.x.

Tuesday, November 17, 2009

St. John's Wort and Perimenopause by Dr Tori Hudson

This double-blind, randomized clinical trial, studied the effect of Hypericum perforatum extract (St. John’s wort extract) compared with placebo, on symptoms and quality of life of 47 symptomatic perimenopausal women aged 40 to 65 with three or more hot flashes per day. Women were randomly assigned to receive a St. John’s wort extract (900 mg three times per day) or placebo. The women used a daily diary to record hot flash severity and frequency during the week before the study group selection process and again for a week before the end of the three month follow-up. The Menopause-Specific Quality of Life questionnaire was also used.

RESULTS: After 12 weeks of treatment, a non-significant difference in favor of the St. John’s wort group was observed in the daily hot flash frequency and the hot flash score. However, after those three months of treatment, women in the St. John’s wort group reported significantly better quality of life scores, and significantly fewer sleep problems compared to placebo.

Commentary: St. Johns wort research is expanding into the realm of use for perimenopause and menopause symptoms. Other recent studies have reported improvement in psychological, well-being and quality of life in symptomatic perimenopausal and menopausal women. In the current study, while not especially helpful for hot flashes, there was an improvement in quality of life scores and sleep problems. I commonly use St. Johns wort with black cohosh for women with hot flashes and mood issues during perimenopause and menopause. The research on each and even two studies using the combination of the two reveal that these two plants in combination are a premium option for perimenopausal and menopausal women with some of the most common of symptoms.

For more information on St. John's Wort http://www.naturalhi.com/Products/StJohnsWort.aspx

For more blogs, information and events with Dr Hudson preseting please go to http://drtorihudson.com/

Reference
Al-Akoum M, Maunsell E, Verreault R, Provencher L, Otis H, Dodin S. Effects of Hypericum perforatum (St. John’s wort) on hot flashes and quality of life in perimenopausal women: a randomized pilot trial. Menopause. 2009 Mar-Apr;16(2):307-14